Ingemuva:
Umhla lu-1 kuZibandlela wezi-2022 wuSuku Lwengculazi Lomhlaba lwama-35.
NgoJulayi 2022, idatha yakamuva evela ku-UNAIDS,2022 Global AIDS Umbiko Wenqubekelaphambili: Amalunga Abalulekileyabonisa ukuthi inqubekelaphambili ekubhekaneni nobhubhane lwengculaza imile kule minyaka emibili edlule, abantu abangu-650,000 emhlabeni wonke basabulawa izifo ezihlobene nengculaza (isilinganiso sokufa okukodwa ngomzuzu), cishe abayizigidi ezingu-1.5 abangenwa yi-HIV (isibalo esiyizigidi ezingu-1 ngaphezu kwalokho okuhlosiwe emhlabeni jikelele), kanye nesimo somhlaba jikelele sokuvinjelwa nokulawulwa kwe-AIDS sisalokhu sishubile.
Yini i-HIV?
I-Human immunodeficiency virus (HIV) igciwane lesandulela ngculaza elidluliselwa ngocansi elingaholela ekutholeni i-immunodeficiency syndrome (AIDS), isimo esiholela ekuhlulekeni kancane kancane kwamasosha omzimba.Ngokwezinkomba zomtholampilo, amaseli e-CD4 + T egazini lomuntu angaphezu kuka-200 anegciwane lesandulela ngculaza, futhi angaphansi kwama-200 ahlulelwa ngokuqondile njengeziguli ze-AIDS.
Kunezinhlobo ezimbili ezinkulu ze-HIV, uhlobo 1 (HIV-I) kanye nohlobo 2 (HIV-II).Amagciwane e-HIV-I aphinde ahlukaniswe abe amagciwane uM, N, O, kanye ne-P. M ayisigaba esivame kakhulu futhi ayimbangela eyinhloko yobhubhane lwengculazi.Amagciwane e-Class O, “O” amele “ama-outliers”.
I-HIV inezindlela ezintathu zokudlulisela, ukusulelana ngokocansi, ukudluliswa kwegazi kanye nokudluliselwa kwengane isuka kumama isiya enganeni.Phakathi kwemizila yokudluliselana ngocansi, ukusulelana nge-HIV ngocansi lwezitabane kungenzeka kakhulu.
Awukho umuthi wokugomela ingculazi osebenzayo.Nakuba imithi elwa namagciwane ekhona ingalicindezela futhi ibambezele ngokuphumelelayo ukuqhubekela phambili kwesifo, imithi ekwazi ukwelapha ingculaza ngokuphelele ayikatholakali.
Ukuxilongwa
Ukuxilongwa kwaselabhorethri kuwukuphela kwendlela yokuqinisekisa ukutheleleka nge-HIV, futhi izimpawu ezithile ze-serological zingatholwa ekuqaleni kwesikhathi sokutheleleka:
I-HIV RNA: itholwa ngezindlela zamangqamuzana, izinsuku eziyi-11 ngemuva kokutheleleka nge-HIV
I-antigen ye-HIV-I P24: iyabonakala ezinsukwini eziyi-16 ngemuva kokutheleleka
I-antibody ye-HIV: itholakala ezinsukwini ezingama-22 zokutheleleka.
Ezigabeni zokuqala zokutheleleka (i-acute retrovirus syndrome), izimpawu ezinjengomkhuhlane zihambisana nokuphindaphinda kwegciwane okungazelelwe, okungatholakala egazini.Ukutholwa kwe-P24 antigen (i-viral capsid protein) kuhlobene ngqo nenani lamagciwane azungezayo (i-viral load) kubantu abanaleli gciwane.
Amasosha omzimba amelene namaprotheni athile e-HIV nama-glycoprotein (isb, p24, gp41, gp120) akhiqizwa emavikini angu-2-8 ngemva kokutheleleka futhi ayabonakala egazini ngemva kwalokho.
Ukuhlola okusetshenziswa kakhulu ukuthola ukuchayeka kwe-HIV “ukuhlolwa kwe-HIV antibody”.Ukuhlolwa kokuqala kwagunyazwa yi-FDA ngo-1985 futhi kusengenye yezindlela ezinconyiwe ze-WHO zokuxilonga i-HIV.Ukuthuthuka kwezobuchwepheshe kanye nama-reagents abalulekile kuye kwasiza ukuthuthukiswa kokuhlolwa kwe-HIV kwesizukulwane esilandelayo ukuze kutholakale ngokushesha futhi kunembe kakhudlwana abantu abanaleli gciwane.Ukuhlolwa kwe-HIV yesizukulwane sesine kukwazi ukuhlonza ukutheleleka nge-HIV emasontweni ama-3-4 ngemva kokudlulisela ngokuthola kokubili amasosha omzimba we-HIV kanye ne-p24.
Yini engahlinzekwa yi-Bio-Mapper?
Ithimba lezobuchwepheshe le-Maiyue Bio-Mapper lizinikele ocwaningweni nasekuthuthukisweni kwe-HIV antigen & antibody iminyaka eminingi futhi lakhangisa ngempumelelo uchungechunge lwemikhiqizo.Ngokungeziwe ekunikezeni izinto zokusetshenziswa ngegazi njengesampula yokuhlola futhi esebenza kuplathifomu ye-Immunochromatography/Flurescence Chromatography, i-Bio-Mapper inekhono lokuhlinzeka ngezinto ezingasetshenzisiwe ze-antigen/antibody ezisebenza kuplathifomu ye-ELISA/Plate Luminescence, ngisho nenkundla ye-Tubular Magnetic Particle Chemiluminescence.Umugqa womkhiqizo we-Maiyue Bio-Mapper ucebe ngokwedlulele.
I-HIV Engcono Kakhulu (Esheshayo) Umkhiqizi kanye Nomkhiqizi |I-Bio-mapper (mapperbio.com
I-HIV Engcono Kakhulu (CMIA) Ithekelisa kanye Nomkhiqizi |I-Bio-mapper (mapperbio.com)
I-HIV Engcono Kakhulu (CMIA) Ithekelisa kanye Nomkhiqizi |I-Bio-mapper (mapperbio.com)
I-HIV Engcono Kakhulu (Abanye) Umthengisi kanye Nomkhiqizi |I-Bio-mapper (mapperbio.com)
Izindlela ezintathu zokudlulisela i-HIV zibalulwe ngenhla, kanti i-HIV, i-antigen ye-HIV, ibonakala ngobuningi esidodeni, ekuphumeni kwesitho sangasese sowesifazane, uketshezi lwe-preseminal, uketshezi lwe-rectal, igazi, nobisi lwebele.Kodwa-ke, igciwane lesandulela ngculaza alikho emchamweni wabantu abane-HIV, futhi amanani amancane kakhulu egciwane lesandulela ngculaza angase abekhona ematheni, amanani alandelela ngokwedlulele ukuze kudalwe ukutheleleka.
Nakuba ama-antigen e-HIV engekho noma ekhona ngamanani amancane kakhulu emchameni nasematheni, amanani athile amasosha omzimba e-HIV angatholwa kukho kokubili umchamo namathe abantu abane-HIV.
I-antigen recombinant ehlinzekwa yi-Maiyue Bio-Mapper ingasetshenziswa ukuthola amasosha omzimba e-HIV emchameni nasematheni.Phakathi kwalokhu, indawo ye-gp41 ibona amasosha omzimba abopha i-HIV-1 futhi i-gp36 isetshenziselwa ukubona amasosha omzimba anoveli ahlanganisa i-HIV-2.Ukuhlolwa komchamo we-HIV okudala inkathi nemikhiqizo yokuhlola amathe kusiza izikhungo zokunakekelwa kwezempilo ukuthi zenze ukuhlolwa kokuqala kwe-HIV ngokushesha nangempumelelo.Ngenxa yokuthi umuntu ozohlolwa angakwazi ukuqoqa amasampula amathe nomchamo ngokwakhe, umkhiqizo ungasetshenziselwa ukuzihlolela ekhaya, okwenza kube lula kakhulu.Ngesikhathi esifanayo, ngenxa yokuthi ukuhlolwa akukona ukuhlasela futhi akunalo igazi (inani le-HIV egazini likhulu futhi ingozi yokudlulisela i-AIIDS iphezulu kakhulu), ngeke kube khona inkinga "yokutheleleka", kanye nengozi yokutheleleka. komhloli noma abasebenzi bezokwelapha, ubungozi bokuchayeka emsebenzini kwabasebenzi abathatha amasampula, kanye nengozi yokutheleleka ngemfucuza yezokwelapha nakho kungagwenywa.
Isiphetho:
Anti-ubhubhane, anti-AIDS ngaphezu.Imikhiqizo kaMaiyue Bio-Mapper yokuhlola i-HIV izokwazi ukufaka isandla ngamandla amancane esibangeni sokulawula ingculaza emhlabeni wonke!
Ireferensi:2022 Global AIDS Umbiko Wenqubekelaphambili: Amalunga Abalulekile
Isikhathi sokuthumela: Dec-12-2022