Ulwazi oluyisisekelo
| Igama Lomkhiqizo | Ikhathalogi | Uhlobo | Umsingathi/Umthombo | Ukusetshenziswa | Izinhlelo zokusebenza | I-Epitope | I-COA |
| I-HEV Antigen | I-HEV Antigen | I-Antigen | E.coli | Thwebula | CMIA, WB | / | Landa |
| I-HEV Antigen | I-BMIHEV012 | I-Antigen | E.coli | Hlanganisa | CMIA, WB | / | Landa |
| I-HEV Antigen | BMIHEV021 | I-Antigen | E.coli | Thwebula | CMIA, WB | / | Landa |
| I-HEV Antigen | I-BMIHEV022 | I-Antigen | E.coli | Hlanganisa | CMIA, WB | / | Landa |
Umzila wokudluliselwa kwesifo sokusha kwesibindi kohlobo E (ikakhulukazi ngomzila womlomo we-fecal) kanye nokuvela komtholampilo (ukutheleleka okuphindaphindekayo, ukusha kwesibindi kokuqina, ukusha kwesibindi kohlobo olungapheli, njll.) kuyafana naleyo ye-hepatitis A. Isifo sokusha kwesibindi kohlobo E siphezulu kubantu abasha nakubantu abadala. iminyaka engu-15-39.I-Hepatitis E nayo iyisifo esizimele.I-HEV futhi ayinawo umphumela oqondile we-pathological (CPE) kuma-hepatocyte.Umzimba ungathola amasosha omzimba athile ngemva kokugula, kodwa awuzinzile ngokwanele.Kunomuthi wokugomela i-hepatitis E, futhi izinyathelo zokuvimbela isifo sokusha kwesibindi kohlobo E ngokuyinhloko zihlanganisa ukunqanyulwa komzila wokudluliselwa komlomo we-fecal.
I-HEV ikhishwa ngendle yeziguli, isatshalaliswa ngokuthintana kwansuku zonke, futhi ingasatshalaliswa noma kuqubuke ubhubhane olubangelwa ukudla okungcolile nemithombo yamanzi.Isilinganiso esiphezulu sezigameko ngokuvamile sisenkathini yemvula noma ngemva kwezikhukhula.Isikhathi se-incubation singamaviki angu-2 ~ 11, kanye nesilinganiso samaviki ayisi-6.Iningi leziguli zasemtholampilo zinesifo sokusha kwesibindi esimaphakathi kuya komaphakathi, esivame ukuzikhawulela, futhi asithuthuki sibe yi-HEV engapheli.Ihlasela kakhulu abantu abasha, abangaphezu kuka-65% abaneminyaka yobudala ephakathi kwe-16 kuya kweyi-19 ubudala, futhi izingane zinezifo eziningi ezingaphansi komtholampilo.
Izinga lokufa kwabantu abadala lingaphezulu kwelesifo sokusha kwesibindi kohlobo A, ikakhulukazi kwabesifazane abakhulelwe abaphethwe yisifo sokusha kwesibindi kohlobo E, kanti izinga lokushona kwabantu abangenwe yileli gciwane ezinyangeni ezintathu ezedlule lingama-20%.
Ngemuva kokutheleleka nge-HEV, ingakhiqiza ukuvikeleka kwamasosha omzimba ukuze kuvikelwe i-HEV yokutheleleka kabusha kohlobo olufanayo noma uhlobo oluhlukile.Kubikwa ukuthi i-anti-HEV antibody ku-serum yeziguli eziningi ngemva kokuvuselelwa ihlala iminyaka engu-4-14.
Ukuze kuhlolwe ukuhlolwa, izinhlayiya zegciwane zingatholakala endle ngesibonakhulu se-electron, i-HEV RNA ku-bile bile ingatholwa yi-RT-PCR, kanti amasosha omzimba e-anti HEV IgM kanye ne-IgG ku-serum angatholwa yi-ELISA esebenzisa i-HEV glutathione S-transferase fusion. amaprotheni njenge-antigen.
Ukuvimbela okuvamile kwe-hepatitis E kuyafana nalokho kwe-hepatitis B. Ama-immunoglobulins avamile awasebenzi ekugomeni okuphuthumayo okuphuthumayo.
